Project Overview:
  
  Spray drying has been successfully used for the encapsulation of herbal bioactive compounds, resulting in stable phytopharmaceutical formulations, which is a South American medicinal plant with antimalarial, hepatoprotective, and antioxidant activities, usually associated with its secondary metabolites, flavonoids and polyacetylenes.
  
Project Operation:
  
  In this work, the physicochemical stability of an optimized spray-dried composition from aB was evaluated in open containers and sealed sachets under three different stress storage conditions for a follicular extract. The concentrations of three marker compounds were monitored by HPLC over 12 months, and color changes of stored samples were assessed using a color spectrophotometer.
  
Project Testing and Results:
  
  It was observed that the concentrations of the monitored phytochemicals decreased more severely in samples stored in open containers. The degradation rates of the two monitored flavonoids, rutin and hyperoside, were lower than that of polyacetylenes. The concentrations of markers did not change significantly at low temperatures. Regarding color, darker hues were observed at higher temperatures and longer storage times.
  
  This study shows that storage conditions have a significant impact on the stability of standard spray-dried B.